The EU began as a noble concept. Unfortunately, it has consistently got the economics wrong, thereby sowing the seeds of its ultimate disintegration. The EU gave us VAT, CAP, a tariff wall and expensive food. It would be difficult to conceive of a worse combination, apart from capping them with a common currency. Bearing in mind that all taxes apart from LVT amplify the effects of locational disadvantage, it is not surprising that support for Brexit came from the country's margins, not excluding parts of the South-East. This is not to suggest that those who voted to leave were making a reasoned and calculated choice. At that level it was a gut reaction, with nasty overtones. However, if one neglects one's back garden, weeds will grow. Some, such as knotweed, can undermine a house. The UK has neglected its fringes for many decades.
The first of the ugly sisters is VAT.